Endocytosis takes occludin for a ride
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Endocytosis takes occludin for a ride
T he lining of the small intestine locks out bacteria and toxins while soaking up nutrients and water. By observing intestinal cells of live mice through the microscope, Marchiando et al. (1) reveal the mechanism that regulates this barrier. The study shows the importance of the tight junction protein occludin for the process and identifi es the endocytic route that removes occludin to adjust p...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2010
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1891if